20-P024 Role of Notch and its targets in regulating migration and morphogenesis
نویسندگان
چکیده
dered if guidance cue-induced changes in NFPC protein synthesis may play a role here. Interestingly, stimulating cultured growth cones with Sema3A, a repellent molecule expressed in telencephalic regions adjacent to the MOT, elevates NFPC protein twofold within 10 min. Therefore, we now postulate a growth cone turning mechanism involving Sema3A-induced increases in TAF1mediated NFPC activity at the MOT choice point.
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ورودعنوان ژورنال:
- Mechanisms of Development
دوره 126 شماره
صفحات -
تاریخ انتشار 2009